Genetic Factors Underlying Susceptibility to Acute Pyelonephritis and Post-infectious Renal Damage
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Complicated bilateral fungal emphysematous pyelonephritis in a 55-year-old diabetic female: A case report and review of literature
Background and Purpose: Emphysematous pyelonephritis (EPN) is a rare and serious disease causing acute renal failure. Diabetes is a major risk factor for this infection. Case report: Herein, we present the case of a 55-year-old female patient with diabetes and EPN caused by Candida albicans. The infection was complicated with endophthalmitis and endocarditis. The results of antifungal suscep...
متن کاملتعیین میزان گرفتاری پارانشیم کلیه با استفاده از سنتی گرافی قشر کلیه (اسکن DMSA) در کودکان مبتلا به پیلونفریت حاد مرکز طبی کودکان، 80-1379
Background: Urinary tract infection is a common bacterial infection in children and may lead to irreversible renal damage. TC 99-m Dimercaptosuccinic acid renal scintigraphy is the most sensitive method for diagnosing acute pyelonephritis. We designed a study to evaluate the ability of DMSA scan and ultrasonography to detect renal paranchymal lesion. Materials and Methods: 62 children 1 month t...
متن کاملDoppler ultrasonography in children with acute pyelonephritis in diagnosis of renal scar compared to DMSA scintigraphy
Background: Urinary tract infection (UTI) is one of the most important pediatric health problems, which is occasionally associated with irreversible renal damage. Dimercapto-succinic acid (DMSA) scan is a diagnostic standard for the renal scar. Doppler ultrasonography (D.S) has been considered as a less invasive method. The purpose of this study was to determine the sensitivity and specificity ...
متن کاملA Genetic Basis of Susceptibility to Acute Pyelonephritis
BACKGROUND For unknown reasons, urinary tract infections (UTIs) are clustered in certain individuals. Here we propose a novel, genetically determined cause of susceptibility to acute pyelonephritis, which is the most severe form of UTI. The IL-8 receptor, CXCR1, was identified as a candidate gene when mIL-8Rh mutant mice developed acute pyelonephritis (APN) with severe tissue damage. METHODS ...
متن کاملRisk factors of renal scars in children with acute pyelonephritis.
OBJECTIVE The aim of this study was to determine the association between previously documented risk factors such as recurrent pyelonephritis with the incidence of renal scarring after acute pyelonephritis in children. MATERIAL AND METHODS Children with acute pyelonephritis who were admitted to the Department of Pediatrics of a teaching hospital during 2007-2009 were enrolled in this study. DM...
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